Minor (2)calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. I. Use Caution/Monitor. Human studies not conducted. )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Applies only to oral form of both agents. Avoid or Use Alternate Drug. By taking into account the case of a patient weighing 78 kg (172 lbs) and having a hemoglobin level of 11 g/dL (110 g/L or 6.83 mmol/L). Here are the steps to follow for using this drug dosage calculator: First, enter the value of your Weight and choose the unit of measurement from the drop-down menu. Applies only to oral form of both agents. Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Venofer. Accessed: 4/12/2011. Anemia; 2015: 763576. vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Anemia. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Dosage: For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. For additional Safety Information, please see Full Prescribing Information. Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD): Administer Venofer 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl x 15 minutes. 1990 Feb;24(2):162-6. Each costs about $0.46 to $0.55 per mg of iron. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Applies only to oral form of both agents. Use Caution/Monitor. Avoid or Use Alternate Drug. ANNA J. Use Caution/Monitor. 5. Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Venofer has not been studied in patients younger than 2 years old. Applies only to oral form of both agents. calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. There are four variables, all patient parameters, required in the iron deficiency calculator: The patients weight is used in the Ganzoni equation and also when establishing the iron stores. This parenteral iron replacement for iron deficiency anemia calculator determines the parenteral dose of iron supplement needed to replenish iron stores and hemoglobin levels. All you have to do is use the following formula: Liquid\ dose = Dose / Medicine\ concentration Liquid dose = Dose/M edicine concentration. deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. Monitor Closely (1)iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Serious - Use Alternative (1)iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Oral and parenteral products - see background option for oral products. Venofer treatment may be repeated if necessary. Hollands J, Foote E, Rodriguez A. Applies only to oral form of both agents. Iron Deficiency Anemia: Periodic hematologic determination (hemoglobin and hematocrit) is a simple and accurate technique for monitoring hematological response, and should be used as a guide in therapy. calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Avoid or Use Alternate Drug. The Ganzoni equation is: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron - carboxymaltose); Iron sucrose (Venofer) 100 mg/5 mL vial 200 - 300 mg given every 3-7 days 300 mg doses are given over 90 minutes 500 mg/dose. 1970; 100(7):301-3. Deferasirox chelates iron. Modify Therapy/Monitor Closely. The dosage of Venofer is expressed in mg of elemental iron. UpToDate. This site contains information for licensed healthcare professionals in the United States. Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL * Adapted from the KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease. Jacobs P, Dommisse J. Monitor Closely (1)iron sucrose decreases levels of ibandronate by inhibition of GI absorption. Minor/Significance Unknown. If no signs or symptoms of anaphylactic-type reactions follow the test dose, administer the full therapeutic INFeD dose. Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events. Applies only to oral form of both agents. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. You are encouraged to report Adverse Drug Events to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Multiple placebo-controlled, randomized clinical trials have been conducted with IV iron in patients with New York Heart Association class II-III heart failure with an ejection fraction 45% who met criteria . Applies only to oral form of both agents. You can further save the PDF or print it. Applies only to oral form of both agents. Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Diagnosis and management of iron deficiency anaemia: a clinical update. Use Caution/Monitor. We comply with the HONcode standard for trustworthy health information. feasible, Maximum total cumulative iron sucrose dose administered in 14 days is 1000 mg elemental iron. Always ask your health care professional for complete information about this product and your specific health needs. Kumpf VJ. Applies only to oral form of both agents. Use Caution/Monitor. Use Caution/Monitor. Applies only to oral form of both agents. . Use Caution/Monitor. Applies only to oral form of both agents. Interaction only with oral iron administration. During all INFeD administrations, observe for signs or symptoms of anaphylactic-type reactions. Feraheme, when added to intravenous infusion bags containing either 0.9% Sodium Chloride Injection, USP (normal saline), or 5% Dextrose Injection, USP, at concentrations of 2-8 mg elemental iron per mL, should be used immediately but may be stored at controlled room temperature (25C 2C) for up to 4 hours or refrigerated (2-8 C) for up to 48 hours. Applies only to oral form of both agents. HOW TO USE: This medication is given by injection into a vein as directed by your doctor. Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)- . For patients receiving hemodialysis, administer Feraheme once the blood pressure is stable and the patient has completed at least one hour of hemodialysis. Modify Therapy/Monitor Closely. in the colostrum of 10 iron deficient breastfeeding women who were 2 to 3 days postpartum and received a single dose of 100 mg of intravenous iron . Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely. [. iron sucrose increases levels of calcium acetate by enhancing GI absorption. Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. Monitor patients for signs and symptoms of hypersensitivity during and after Venofer administration for at least 30 minutes and until clinically stable following completion of the infusion. Applies only to oral form of both agents. 3) Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. (1988) Clinical use of the total dose intravenous infusion of iron dextran. The dosage of Venofer is expressed in mg of elemental iron. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: vitamin products, other iron-containing products. Assessing new treatment options, Intravenous iron-dextran: therapeutic and experimental possibilities. The recommended dosage of iron sucrose for repletion of iron deficiency in patients undergoing hemodialysis is 5ml of iron sucrose (100mg of elemental iron) delivered intravenously during the dialysis session. . Suggested regime: Prescribing instructions Prescribing a single/first dose: Andreas M. Ganzoni, MD, is a physician and researcher in the internal medicine department at the University of Zurich in Zurich, Switzerland. The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. Use Caution/Monitor. Test Dose: Not required. Use Caution/Monitor. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Calcs that help predict probability of a disease, Subcategory of 'Diagnosis' designed to be very sensitive, Disease is diagnosed: prognosticate to guide treatment. Modify Therapy/Monitor Closely. https://www.uptodate.com/ (Requires subscription). Use Caution/Monitor. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Venofer (iron sucrose injection, USP) For Intravenous Use Only INDICATION AND USAGE Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Assessing new treatment options. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin, Do not mix with other medications or add to parenteral nutrition solutions for IV infusion, Do not dilute to concentrations below 1 mg/mL, Add dose to 0.9% NaCl infusion bags (PVC or non-PVC); final concentrations range is 1-2 mg of elemental iron/mL, Visually inspect for particulate matter and discoloration prior to infusion, Stable for 7 days at controlled room temperature (25C). Monitor Closely (1)vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. . Administer Venofer only intravenously by slow injection or by infusion. Use Caution/Monitor. No additional iron to replenish stores. Do not mix iron sucrose with other medications or TPN solution. Calculation of Dosage of Nefrofer Total Iron Deficit (mg) Nefrofer (ml) = 20mg/ml Total Iron Deficit (mg) = Body weight (kg) x (Target Hb - Actual Hb) [g/l] x 0.24* + Depot Iron . Administer a test INFeD dose prior to the first therapeutic dose. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. Corrected Calcium. iron sucrose increases levels of calcium citrate by enhancing GI absorption. ADMINISTER THE TEST DOSE AT A GRADUAL RATE OVER AT LEAST 30 SECONDS. Step 2: Calculation and administration of the maximum individual iron dose(s): . Applies only to oral form of both agents. Use Caution/Monitor. In this study and another study evaluating a single intravenous dose of iron sucrose containing 500-700 mg of iron in 26 anemic patients on erythropoietin therapy (23 female, 3 male; age range 16-60), approximately 5% of the iron was . May increase risk of hypotension. Minor/Significance Unknown. Applies only to oral form of both agents. There is in depth information below the form on the method used and on the result provided. iron sucrose decreases levels of deferiprone by enhancing GI absorption. Where C= concentration of iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. Venofer treatment may be repeated if iron deficiency reoccurs. The original formula employs the weight in kg but users can input it in lbs and it gets transformed. Accessed: 4/12/2011. Contraindicated. Venofer may cause clinically significant hypotension. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 Hb in g/dL) x 2.145, Volume of product required in mL = Iron deficit in mg / C in mg/mL. Otherwise, call a poison control center right away. iron sucrose decreases levels of minocycline by inhibition of GI absorption. Applies only to oral form of both agents. Serious - Use Alternative (1)iron sucrose decreases levels of minocycline by inhibition of GI absorption. Applies only to oral form of both agents. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. Applies only to oral form of both agents. Applies only to oral form of both agents. It is important to note that the above calculations merely provide estimates and that individual dosage should be established by a medical professional based on the current package insert for the elemental iron product used. This topic . iron sucrose increases levels of calcium chloride by enhancing GI absorption. Administer Venofer early during the dialysis session (generally within the first hour). Safety of highdose iron sucrose infusion in hospitalized patients with chronic kidney disease. The recommended Feraheme dose may be readministered to patients with persistent or recurrent iron deficiency anemia. Monitor Closely (1)deferasirox decreases levels of iron sucrose by inhibition of GI absorption. 1. Dose administration to an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Use Caution/Monitor. Applies only to oral form of both agents. Slow or stop the infusion if adverse reactions occur. To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. Treatment of anemia due to iron deficiency. Minor (1)gymnema decreases levels of iron sucrose by inhibition of GI absorption. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Each mL contains 20 mg of elemental iron. Minor/Significance Unknown.iron sucrose increases levels of calcium chloride by enhancing GI absorption. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). (1970) Intravenous iron-dextran: therapeutic and experimental possibilities. For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. 1 ,*. The plasma ferritin level as a reliable index of body iron stores following intravenous iron dextran. LBW = Lean body weight in kg. This information is not individual medical advice and does not substitute for the advice of your health care professional. Avoid or Use Alternate Drug. Ferumoxytol [ Feraheme ] Elemental iron: 510 mg/17 mL (17 mL) 30 mg/mL [package insert] - Boxed warning REVIEW INSERT. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. Recommended dosing and infusion rates for PI. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Intravenous iron-dextran: therapeutic and experimental possibilities. Hemodialysis-dependent: 0.5 mg/kg IV q2weeks for 12 weeks; not to exceed 100 mg/dose, Non-dialysis dependent or peritoneal-dependent (on erythropoietin): 0.5 mg/kg IV q4weeks for 12 weeks; not to exceed 100 mg/dose, sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, Serious hypersensitivity reactions reported, including anaphylactic-type reactions, some of which have been life-threatening and fatal, Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse, If hypersensitivity reactions or signs of intolerance occur during administration, stop infusion immediately, Monitor patients for signs and symptoms of hypersensitivity during and after administration for at least 30 minutes and until clinically stable following completion of the infusion, Animal reproduction studies of iron sucrose administered to rats and rabbits during period of organogenesis at elemental iron doses equivalent to maximum recommended human dose based on body surface area revealed no evidence of harm to the fetus; adverse outcomes in pregnancy occur regardless of health of mother or use of medications, Iron deficiency anemia during pregnancy should be treated; untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia; adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight, HD-dependent and non-dialysis-dependent CKD: Dilute with up to 100 mL of 0.9% NaCl, PD-dependent CKD: Dilute with up to 250 mL of 0.9% NaCl, Undiluted: Administer by slow IV injection over 2-5 min, Diluted solutions: Administer IV over 15 min, Undiluted: Administer by slow IV injection over 5 minutes, Diluted solutions: Administer IV over 5-60 minutes, Store in original carton at 20-25C (68-77 F); excursions permitted to 15- 30C (59-86F), Syringe: Store at room temperature (25C) or under refrigeration (4C) for up to 7 days, IV infusion: Store at room temperature (25C) for up to 7 days. Contact the applicable plan FOR PATIENTS WEIGHING LESS THAN 50 kg: Administer Monoferric as 20 mg/kg actual body weight by intravenous infusion 20 minutes . Applies only to oral form of both agents. This website is intended for use by US healthcare professionals only. Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. Use Caution/Monitor. Avoid or Use Alternate Drug. Applies only to oral form of both agents. In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Burns DL, Mascioli EA, Bistrian BR. Applies only to oral form of both agents. The initial hemoglobin rise is more rapid with parenteral iron but on the long term (12 weeks), both therapies reach similar levels of hemoglobin. Below the form there are further instructions on how to use the calculator. Avoid or Use Alternate Drug. The factor 2.4 is derived from the following assumptions: a) Blood volume 70 ml/kg of body weight ~7% of body weight b) Iron content of hemoglobin 0.34% Factor 2.4 = 0.0034 x 0.07 x 10000 (conversion for g/dL) Ganzoni AM. If either is present, do not use the liquid. Applies only to oral form of both agents. Applies only to oral form of both agents. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Separate by at least 4 hours. Applies only to oral form of both agents. Venofer treatment may be repeated if iron deficiency reoccurs. Feraheme does not contain antimicrobial preservatives. Corrected Sodium and Effective Osmolality. The dosage of Venofer is expressed in mg of elemental iron. The dosage of Venofer is expressed in mg of elemental iron. The dosage of iron sucrose is expressed in mg of elemental iron. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. INFeD is given undiluted at a slow gradual rate not to exceed 50 mg (1 mL) per minute. View the formulary and any restrictions for each plan. *Repeat dose if iron deficiency anemia reoccurs. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . Drug class: Iron products. Formula for calculating the required dose of iron sucrose 1. Diluted with 0.9% Sodium Chloride Injection at concentrations of 1 to 2 mg/mL, 2 doses of 300 mg/250 mL over 1.5 hrsplus1 dose of 400 mg/250 mL over 2.5 hrs. Fatal reactions have also occurred in situations where the test dose was tolerated. Calculation of total iron deficit for initial repletion: [29] Total cumulative dose (mg) = [Target Hb Actual Hb] weight (kg) 2.4 + [15 weight (kg)] *Hb in g/dl: 2. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. This site complies with the HONcode standard for trust- worthy health information: verify here. Avoid or Use Alternate Drug. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Use Caution/Monitor. Applies only to oral form of both agents. Minor/Significance Unknown. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Drug: Comments: A: Acyclovir 1: Dose using a 40% adjusted body weight; Amikacin 2: Dose using a 40% adjusted body weight; Amphotericin B (liposomal) 3 Consider capping body weight to 100 kg; Atracurium 4: Dose using ideal body weight; The use of ideal body weight has been shown to be associated with a more predictable muscle strength recovery within 60 minutes and a lack of need for antagonism . Copyright(c) 2023 First Databank, Inc. Challenges in the treatment of iron deficiency include finding and addressing the underlying cause and the selection of an iron replacement product that meets the needs of the patient. iron sucrose will decrease the level or effect of omadacycline by inhibition of GI absorption. Monitor Closely (1)didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. The following table present normal hemoglobin ranges: There is another equation for iron deficit that can be used to calculate replenishment needs, that of Ganzoni, which takes into account iron stores as well and that can be found in the iron deficit calculator. 3. Access your plan list on any device mobile or desktop. You may report side effects to Health Canada at 1-866-234-2345. In case a pediatric patient with a weight below 35 kg is assessed, iron stores are calculated as 15 mg iron for each kg. Parenteral iron product is iron sucrose (C = 20 mg elemental iron/mL). Comparable efficacy to that of IV iron sucrose. This document does not contain all possible drug interactions. gymnema decreases levels of iron sucrose by inhibition of GI absorption. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 - Hb in g/dL) x 2.145 Volume of product required in mL = Iron deficit in mg / C in mg/mL Where C is the concentration of the iron product: 50 mg/mL for Iron dextran; 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. The weight of the patient is taken into account in order to estimate iron stores, while haemoglobin is required as both current measured and target. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Parenteral Iron Replacement For Iron Deficiency Anemia Calculator, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Clinical use of the total dose intravenous infusion of iron dextran, When is high-dose intravenous iron repletion needed? Controlled studies in pregnant women show no evidence of fetal risk. IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. Monitor Closely (1)sodium bicarbonate will decrease the level or effect of iron sucrose by increasing gastric pH. A: Generally acceptable. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. No data are available regarding overdosage of Venofer in humans. (See also Notes section. Applies only to oral form of both agents. Applies only to oral form of both agents. (1970) Intravenous iron-dextran: therapeutic and experimental possibilities. The dosage of Venofer is expressed in mg of elemental iron. Injection site discoloration has been reported following extravasation. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. * Calculators are available in UpToDate to determine ideal body weight and lean body weight. iron sucrose decreases levels of manganese by inhibition of GI absorption. Koch TA, Myers J, Goodnough LT. Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. All Rights Reserved. Slowing the infusion rate may alleviate symptoms. Pediatric Patients: The most common adverse reactions (2%) are headache, respiratory tract viral infection, peritonitis, vomiting, pyrexia, dizziness, cough, nausea, arteriovenous fistula thrombosis, hypotension and hypertension. Although the original formula requires the weight in kilograms, values input in lbs are transformed. Minor (2)calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Iron stores 500 mg for body weight greater than or equal to 35 kg (77 lbs) and 15 mg/kg for body weight less than 35 kg. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. These can be input in g/dL, g/L or mmol/L. It is unlikely . Monitor Closely (1)iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Applies only to oral form of both agents. Indications: Ferrlecit is an iron replacement product for treatment of iron deficiency anemia in adult patients and in pediatric patients age 6 years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy. Avoid or Use Alternate Drug. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Treatment of iron deficiency anemia associated with gastrointestinal tract diseases, Diagnosis and management of iron deficiency anaemia: a clinical update. MISSED DOSE: It is important to get each dose of this medication as scheduled. 2.1 . Dosage form: injection, solution Use Caution/Monitor. Monitor Closely (1)pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Medically reviewed by Drugs.com. official version of the modified score here. Other indications for IV are pregnancy iron deficiency, chronic renal impairment or need for rapid repletion. Avoid or Use Alternate Drug. dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Dosing Administration & Considerations . Modify Therapy/Monitor Closely. Fulminant symptoms may include general paleness, confusion or episodes of passing out. Adding plans allows you to compare formulary status to other drugs in the same class. Venofer must only be administered intravenously either by slow injection or by infusion. Philadelphia, PA: Lippincott Williams & Wilkins;2013;303-307. FERAHEME met the predefined criteria for non-inferiority to Venofer . calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. Mean change in Hgb from baseline to Week 5 2,5
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venofer dosing calculator