pfizer xanax 2mg bottle

1 line going down the center of the 2. The following severe adverse reactions have occurred with benzodiazepine abuse and/or misuse: delirium, paranoia, suicidal ideation and behavior, seizures, coma, breathing difficulty, and death. Benzodiazepines interact at gamma-aminobutyric acid (GABA, Limit dosage and duration of concomitant use of XANAX XR and opioids, and monitor patients closely for respiratory depression and sedation. Flumazenil may be useful in situations when an overdose with a benzodiazepine is known or suspected. In some cases, they may not be available in every strength or form as the brand-name version. The mean absolute bioavailability of alprazolam following administration of XANAX XR is approximately 90%, and the relative bioavailability compared to XANAX is about 100%. Abrupt discontinuation or rapid dosage reduction of benzodiazepines or administration of flumazenil, a benzodiazepine antagonist, may precipitate acute withdrawal reactions, including seizures, which can be life-threatening. More severe acute withdrawal signs and symptoms, including life-threatening reactions, have included catatonia, convulsions, delirium tremens, depression, hallucinations, mania, psychosis, seizures, and suicidality. WebThis product information is intended only for residents of the United States. Alprazolam and its metabolites are excreted primarily in the urine. Advise patients, their families and caregivers to look for signs of suicidality or worsening depression, and to inform the patient's healthcare provider immediately [see Warnings and Precautions (5.6)]. The mean T1/2 of alprazolam was 21.8 hours (range: 9.9 to 40.4 hours) in a group of obese subjects. WebThe U.S. In 2020, 52% of the companys revenues came from the United States, 6% came from each of China and Japan, and 36% came from other countries. The PfizerBioNTech COVID-19 vaccine (tozinameran), sold under the brand name Comirnaty, is an mRNA-based COVID-19 vaccine developed by the German company BioNTech. DESCRIPTION The apparent volume of distribution of alprazolam is similar for XANAX XR and XANAX. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue XANAX XR or reduce the dosage [see Dosage and Administration (2.3), Warnings and Precautions (5.3)]. Alprazolam produced no impairment of fertility in rats at doses up to 5 mg/kg per day, which is approximately 5 times the maximum recommended human dose of 10 mg per day based on mg/m2 body surface area. Fertility. Insomnia Is your theme custom made or did you download it from somewhere? The white, rectangle Xanax pill with the imprint X ANA X 2 supplied by Pfizer U.S. Pharmaceuticals Group is a very common brand of alprazolam containing 2mg of the active ingredient. As with the management of intentional overdosing with any drug, it should be borne in mind that multiple agents may have been ingested. WebThe use of benzodiazepines, including XANAX, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. XANAX XR should be reduced to half of the recommended dosage when a patient is started on ritonavir and XANAX XR together, or when ritonavir is added to a patient treated with XANAX XR. Physician Prescribing Information. But if you take several doses per day and miss a dose and its almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Reproductive Health. Short-term low doses of ritonavir (4 doses of 200 mg) increased mean AUC of alprazolam by about 2.5-fold, and did not significantly affect Cmax of alprazolam. -Impaired coordination Misuse is the intentional use, for therapeutic purposes, of a drug by an individual in a way other than prescribed by a health care provider or for whom it was not prescribed. The dosage of Xanax pills ranges from 0.25 milligrams to 3.5 milligrams. I never even stated that the pills are real pharmaceutical grade. The continued use of benzodiazepines, including XANAX XR, may lead to clinically significant physical dependence. Adverse Reactions Occurring at an Incidence of 1% or More Among Patients Treated with XANAX XR. In order to better understand the underground market for this drug, StreetRx collects data on the street price of Xanax and has found that its average black-market price is approximately $7. If a substance use disorder is suspected, evaluate the patient and institute (or refer them for) early treatment, as appropriate. Find out more about the street price of Klonopin (Clonazepam) Xanax (Alprazolam) Xanax is one of the most commonly abused benzodiazepines. Reduce the dosage by no more than 0.5 mg every three days. Death is more often associated with polysubstance use (especially benzodiazepines with other CNS depressants such as opioids and alcohol). Xanax is used to treat anxiety disorders and anxiety caused by depression. It is supplied by Pfizer U.S. Pharmaceuticals Group. If an overdose occurs, consult a Certified Poison Control Center at 1-800-222-1222 for the latest recommendations. Each tablet contains 2 mg alprazolam. Some patients may benefit from an even more gradual discontinuation. It can be used for the short-term relief of symptoms of anxiety, or anxiety linked with depression. No evidence of carcinogenic potential was observed in rats or mice administered alprazolam for 2 years at doses up to 30 and 10 mg/kg/day, respectively. It may harm them. There is positive evidence of human fetal risk during pregnancy. The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-] [1,4] benzodiazepine. for Healthcare professionals: XANAX U.S. Each segment is meant to be a single 0.5 mg dose of Xanax. The recommended dosage range is 3 mg to 6 mg once daily. Published data from observational studies on the use of benzodiazepines during pregnancy do not report a clear association with benzodiazepines and major birth defects. All forms are taken by mouth. WebWomen's Health. WebThe street value of Xanax varies depending on location and the dosage of the pill. Neonates born to mothers using benzodiazepines during the later stages of pregnancy have been reported to experience symptoms of sedation and neonatal withdrawal [see Warnings and Precautions (5.4), Clinical Considerations)]. Xanax is a powerful Benzodiazepine that is often prescribed to treat generalized anxiety disorder (GAD), panic disorders, and insomnia. Physician Prescribing Information. Had a duplicate order which was rectified almost upon receipt of email to customer care .then I had it delivered super fast . Inform patients that the continued use of XANAX XR may lead to clinically significant physical dependence and that abrupt discontinuation or rapid dosage reduction of XANAX XR may precipitate acute withdrawal reactions, which can be life-threatening. This product's labeling may have been updated. It may also be used for other conditions as determined by your doctor. Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia). It is dangerous to purchase Xanax on the Internet or outside the United States. Some of these can be life-threatening, such as seizures. Abrupt discontinuation or rapid dosage reduction of XANAX XR after continued use, or administration of flumazenil (a benzodiazepine antagonist) may precipitate acute withdrawal reactions, which can be life-threatening (e.g., seizures), In some cases, benzodiazepine users have developed a protracted withdrawal syndrome with withdrawal symptoms lasting weeks to more than 12 months, Table 1: Adverse Reactions Leading to Discontinuation in 1% of XANAX XR-treated Patients and at least twice the Rate of Placebo-treated Patients in Placebo-Controlled Trials, General disorders/administration site conditions, Table 2: Adverse Reactions Occuring in 1% in XANAX-treated Patients and Greater than Placebo-treated Patients in 6 and 8 week Placebo-Controlled Trials Panic Disorder, Injury, poisoning, and procedural complications, Musculoskeletal and connective tissue disorder, Respiratory, thoracic, and mediatinal disorders, General disorders and administration site conditions, Musculoskeletal and connective tissue disorders, Respiratory, thoracic, and mediastinal disorders, Table 3: Discontinuation-Emergent Symptom Incidence Reported in 5% of XANAX XR-treated Patients and at least twice the Rate of Placebo-treated Patients in Short-Term, Placebo-Controlled Trials, Respiratory, thoracic and mediastinal disorders, Musculosketal and connective tissue disorders. XANAX XR is indicated for the treatment of panic disorder with or without agoraphobia, in adults. Your healthcare provider can tell you more about the differences between physical dependence and drug addiction. Follow patients for signs and symptoms of respiratory depression and sedation. It is not known if XANAX XR is safe and effective in the treatment of panic disorder for use longer than 8 weeks. Alprazolam is extensively metabolized in humans, primarily by cytochrome P450 3A4 (CYP3A4), to two major active metabolites in the plasma: 4-hydroxyalprazolam and -hydroxyalprazolam. and the best Part is there customer support. Analyses of the relationship between treatment outcome and gender did not suggest any differential responsiveness on the basis of gender. WebXANAX XR is a benzodiazepine indicated for the treatment of panic disorder with or without agoraphobia, in adults. WebThe U.S. In the U.S. general population, the estimated risk of major birth defects and of miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively. The benzodiazepines, including alprazolam, produce additive CNS depressant effects when coadministered with other CNS depressants. Other common Xanax side effects include: Difficulty speaking Problems with coordination See 17 for PATIENT COUNSELING INFORMATION and Medication Guide. The use of benzodiazepines, including XANAX XR, exposes users to the risks of abuse, misuse, and addiction, which can lead to overdose or death. Reduce the digoxin dose if necessary. Protect from light. Because of its CNS depressant effects, patients receiving XANAX XR should be cautioned against engaging in hazardous occupations or activities requiring complete mental alertness such as operating machinery or driving a motor vehicle. There are reports of sedation and withdrawal symptoms in breastfed neonates and infants exposed to alprazolam. Save my name, email, and website in this browser for the next time I comment. Xanax is a powerful Benzodiazepine that is often prescribed to treat generalized anxiety disorder (GAD), panic disorders, and insomnia. Do not crush, chew or break XANAX XR. However, upon extended exposure to ritonavir (500 mg, twice daily for 10 days), CYP3A induction offset this inhibition. Store at controlled room temperature, 20 to 25C (68 to 77F) [see USP]. The most common side effects include mild to moderate pain at the injection site, fatigue, and headaches. In panic disorders 0.5 mg 3 times a day, the daily dose can reach 3-6 mg, the highest daily dose 10 mg. Depending on the response, the dose may be increased at intervals of 3 to 4 days in increments of no more than 1 mg daily. To report SUSPECTED ADVERSE REACTIONS, contact Pfizer Inc. at 1-800-438-1985 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 1 BOTTLE 50 TABS, 2 BOTTLES 100 TABS, 4 BOTTLES 200 TABS, 6 BOTTLES 300 TABS, 8 BOTTLES 400 TABS, Your email address will not be published. The effect of this meal on Tmax depended on the timing of the meal, with a reduction in Tmax by about 1/3 for subjects eating immediately before dosing and an increase in Tmax by about 1/3 for subjects eating 1 hour or more after dosing. Alprazolam exposure was not meaningfully affected in the presence of ritonavir. Ava is a sensor bracelet that tracks your vital signs such as skin temperature and pulse to track your health and send real-time data to the platform. Death has been reported in association with overdoses of alprazolam by itself, as it has with other benzodiazepines. This boosts the activity of a chemical called gamma-aminobutyric acid (GABA). Table 3 shows the incidence of discontinuation-emergent adverse reactions that occurred during short-term, placebo-controlled trials in 5% or more of patients treated with XANAX XR where the incidence in patients treated with XANAX XR was 2 times greater than the incidence in placebo-treated patients. These drugs are often used to treat similar conditions. buy the best quality steroids. Xanax XR is used in the treatment of panic disorder and belongs to the drug class benzodiazepines . Reproductive Health. In a controlled clinical trial in which 63 patients were randomized to XANAX and where withdrawal symptoms were specifically sought, the following were identified as symptoms of withdrawal: heightened sensory perception, impaired concentration, dysosmia, clouded sensorium, paresthesias, muscle cramps, muscle twitch, diarrhea, blurred vision, appetite decrease, and weight loss. How it works Limit dosage and duration of XANAX XR during concomitant use with CNS depressants. Before you take XANAX XR, tell your healthcare provider about all of your medical conditions, including if you: Tell your healthcare provider about all the medicines you take. (, Recommended total daily dosage is 3 mg to 6 mg daily. Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia). Each segment is meant to be a single 0.5 mg dose of Xanax. Do not give XANAX XR to other people, even if they have the same symptoms that you have. Genocide North America 2025: United States of America (Click the graphic above to view the original archived page) COVID-19 Vaccination in the United States of America (to June 2021) 174,234,573 people Take XANAX XR exactly as your healthcare provider prescribed. Also advise patients to avoid use of alcohol or other CNS depressants while taking XANAX XR [see Warnings and Precautions (5.3)]. WebWomen's Health. In addition, the 1 mg and 3 mg tablets contain D & C yellow No. Morphine, buprenorphine, hydromorphone, oxymorphone, oxycodone, fentanyl, methadone, alfentanil, butorpenol, codeine, dihydrocodeine, meperidine, pentazocine, remifentanil, sufentanil, tapentadol, tramadol. if you are also taking itraconazole or ketoconazole; or The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Other common Xanax side effects include: Difficulty speaking Problems with coordination Store at controlled room temperature, 20 to 25C (68 to 77F) [see USP]. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue XANAX XR or reduce the dosage. a history of depression or suicidal thoughts or behavior; Xanax, the brand name for alprazolam, has an average street price of $2 to $20 per tablet, depending on the strength. -Light-headedness (, Use with CYP3A Inducers: Increase the risk of reduced efficacy of alprazolam. Each XANAX Tablet, for oral administration, contains 0.25, 0.5, 1 or 2 mg of alprazolam. A theme like yours with a few simple tweeks would really make my blog jump XANAX XR may harm your unborn baby. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to XANAX XR during pregnancy. Cardiac disorders: Frequent: palpitation; Infrequent: sinus tachycardia, Ear and Labyrinth disorders: Frequent: Vertigo; Infrequent: tinnitus, ear pain, Eye disorders: Frequent: blurred vision; Infrequent: mydriasis, photophobia, Gastrointestinal disorders: Frequent: diarrhea, vomiting, dyspepsia, abdominal pain; Infrequent: dysphagia, salivary hypersecretion, General disorders and administration site conditions: Frequent: malaise, weakness, chest pains; Infrequent: fall, pyrexia, thirst, feeling hot and cold, edema, feeling jittery, sluggishness, asthenia, feeling drunk, chest tightness, increased energy, feeling of relaxation, hangover, loss of control of legs, rigors, Musculoskeletal and connective tissue disorders: Frequent: back pain, muscle cramps, muscle twitching, Nervous system disorders: Frequent: headache, dizziness, tremor; Infrequent: amnesia, clumsiness, syncope, hypotonia, seizures, depressed level of consciousness, sleep apnea syndrome, sleep talking, stupor, Psychiatric system disorders: Frequent: irritability, insomnia, nervousness, derealization, libido increased, restlessness, agitation, depersonalization, nightmare; Infrequent: abnormal dreams, apathy, aggression, anger, bradyphrenia, euphoric mood, logorrhea, mood swings, dysphonia, hallucination, homicidal ideation, mania, hypomania, impulse control, psychomotor retardation, suicidal ideation, Renal and urinary disorders: Frequent: difficulty in micturition; Infrequent: urinary frequency, urinary incontinence, Respiratory, thoracic, and mediastinal disorders: Frequent: nasal congestion, hyperventilation; Infrequent: choking sensation, epistaxis, rhinorrhea, Skin and subcutaneous tissue disorders: Frequent: sweating increased; Infrequent: clamminess, rash, urticaria, Vascular disorders: Infrequent: hypotension, Discontinuation-Emergent Adverse Reactions Occurring at an Incidence of 5% or More Among Patients Treated with XANAX XR. In patients with hepatic impairment, the recommended starting dosage of XANAX XR is 0.5 mg once daily. Thank you usamedzone for delivering the good product, Great service for getting Xanax delivered from international Carrier Services that dont ship directly to Finland. This may be gradually increased if needed and tolerated [see Use in Specific Populations (8.6), Clinical Pharmacology (12.3)]. The following clinically significant adverse reactions are described elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. (5.2) Abrupt discontinuation or rapid dosage reduction of XANAX after XANAX Tablets (alprazolam) are indicated for the management of anxiety disorder (a condition corresponding most closely to the APA Diagnostic and Statistical Manual [DSM-III-R] diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. Sorry, you need to enable JavaScript to visit this website. XANAX XR is a federal controlled substance (C-IV) because it contains alprazolam that can be abused or lead to dependence. Anxiety Disorders The 2-mg dose of alprazolam in a Xanax bar is a heavy dose of the drug. Xanax is used to treat anxiety disorders and anxiety caused by depression. I will recommend it. Take XANAX XR exactly as your healthcare provider tells you to take it. Before prescribing XANAX and throughout treatment, assess each patients risk for abuse, misuse, and addiction. For the most recent prescribing information, please visit www.pfizer.com. Other studied drugs include: Cimetidine: Coadministration of cimetidine increased the maximum plasma concentration of alprazolam by 82%, decreased clearance by 42%, and increased T1/2 by 16%. Get emergency medical help if you have signs of an allergic reaction to Xanax: hives; difficult breathing; swelling of your face, lips, tongue, or throat. See full prescribing information for XANAX XR. This type of Xanax has XANAX clearly imprinted across the surface. An extended-release drug is released slowly into the bloodstream over time. It is authorized for use in people aged 12 years and older in some jurisdictions and for people 16 years and older in other jurisdictions, to provide protection against infection by the SARS-CoV-2 virus, which causes COVID-19. was told they Taste really bitter. In contrast, patients treated with doses of XANAX greater than 4 mg/day had more difficulty tapering to zero dose than those treated with less than 4 mg/day. The extended-release drug is only used to treat panic disorder. Tolerance to XANAX XR may develop from continued therapy. The plasma circulation levels of the two active metabolites after both Xanax XR and Xanax are less than 10% and 4% of the parent, respectively. Pill with imprint XANAX 2 is White Long Bar, Anxiety Disorders. Controlled trials of XANAX XR for the treatment of panic disorder included dosages in the range of 1 mg to 10 mg per day. Generic Name: alprazolam. CIV. WebXanax Alprazolam 1 mg Tablet Bottle 100 Tablets CIV Pfizer 00009009001. WebXANAX (alprazolam) This product information is intended only for residents of the United States. 2. (, The use of benzodiazepines, including XANAX XR, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. Physician Prescribing Information. If an opioid is initiated in a patient already taking XANAX XR, prescribe a lower initial dose of the opioid and titrate based upon clinical response. The structural formula is represented below: Alprazolam is a white crystalline powder, which is soluble in methanol or ethanol but which has no appreciable solubility in water at physiological pH. This helps to produce a calming effect in your brain. WebThis product information is intended only for residents of the United States.

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