This is a dangerous drug. In the morning (Wednesday) I was not able to zip my jeans, brush my hair or other daily activities. I really think the doctors for whatever reason are unable to tell people to eat right and exercise i.e. I was still a little sore, but improving. My recent dexa scan showed a deterioration in bone loss in the last three years so much so that I now have osteoporosis in my hip. Its recommended to take it on an empty stomach first thing in the morning. After trying a variety of non-drug treatments, I went to the doctor in December 1996 with intermittent insomnia and PMS, and asked for some sleeping tablets. Have been on it a yr. Was ok i think, but disabled badly with fatigue anyway, so hard to know. Reading these reports,i am now worried.am 63 & After taking AA 70mg per wkfor 2months,& all the awful side effects mentioned here,consultant wants to try zoledronate yearly infusion. So after a bit of Internet research and finding this site, I will no longer be taking either drug. The strange thing is that as soon as I read: That is exactly the reaction I had years ago to Metoclopramide the anti sickness drug. but from the start have not felt well, stabbing pains dental probs,aching joints,My dentist referred me to a specialist to have 3 teeth removed,but i lost it in the chair so scared ! From then on the amount of activity needed to bring on the symptoms became less and less, to where I am now. Another problem that really concerns me is that my teeth feel rough, as though the surface is eroding. I asked how we would know if it wasnt working, and his reply was that it would be having an effect on my bones after six months and the next scan results would indicate an increased bone density, or not. Now I am not sure what to do. I had to stop immediately and was plunged in to full blown menopause, which has been hell ever since. Very useful thread this thanks everyone. I have an annual blood test at hospital for gluten. Im now in my 70s and am doing my best to stay out of a wheelchair. Dentist now tells me my teeth are not strong enough to hold a bridge again. H411 (50%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment . Alendronate works by slowing down the cells that break . I have osteopenia aged 58 and my sister has osteoporosis aged 65, she was prescribed Alendronic Acid with similar side effects. There are over 200 million people worldwide who have osteoporosis. But it probably has. Stopping this medication means maintaining your bone health and density through lifestyle and diet. Peripheral neuropathy in the hands and fingers. She decided to come off the Alendronic AcidShe really has gone downhill. My lower teeth started getting loose and getting cavities to the point where , in 2011 I had to have the last remaining 6 lower teeth pulled and dentures made. I do wish you the very best As you age, you will notice changes in your body, such as grayed hair, wrinkles, vision problems, and hearing loss. It's harmful if you suddenly stop taking it without a proper assessment from your healthcare provider. As the Corona virus is ongoing we cannot go back to the GP yet, but she is convinced all the aches started after coming off of it!! I have had to keep off coffee, fruit and anything acidic for months, I even tried gaviscon which made me feel sick and had a bloated stomach for 2 hours. I was told I had osteoporosis in 2004 and was put on Fosamax for about 6 months after which I was switched to Actonel. You can only stop taking alendronic acid when your doctor says so. I was prescribed Alendronic Acid 70 mg by my GP a couple of months go due to fracturing my humorous after I tripped me fell. Gave up Alendronic Acid recently after a random chat with a friend! I am interested about the post that said you should only really take for 2 years does anyone else have info on this. I also read from what seems like reliable sources that oesophageal cancer rates go up by 40% and also causes atrial fibrillation in significant numbers . Thank you for all y9our input re: Alendronic Acid. I started taking alendronic acid in January 2009. She used to get upset stomach the day & day after taking them. Hi, I am 47 years old and recently found out I have osteopenia every where and osteoprosis in on of my hips. We would be very interested in accounts of what happens when people take RxISK reports to doctors. Side effects developed gradually. I have even had to report my concern and disappointment and lack of care by both my GP and Dentist. muscle cramps or spasms, a tingling sensation in your fingers or around your mouth - these can be symptoms of low calcium levels in your blood. Ive just been prescribed AA but having read all the posts on this site have decided not to start taking it. Their non-medical use was to soften water in irrigation systems used in orange groves. As a follow up to my earlier post, on Feb 21st 2021, I am still experiencing side effects as a result of the ingestion of 1 biphosphonate Alendronic Acid 70g tablet on Sunday Feb 2nd. I know they say dairy is a good source of calcium but we are not cows and cant absorbe or digest soemthing that is meant for young calves. I expect only the shareholders are enthusiastic about it! Alendronic Acid is used in the treatment of osteoporosis. http://www.ehealthme.com/cs/osteoporosis/drug+intolerance, http://www.ehealthme.com/cs/osteopenia/drug+intolerance, http://www.ehealthme.com/ds/fosamax/drug+intolerance. I had heard of necrosis in the bones before and she had all the symptoms. But its come to my attention that long term , Suddenly not taking or stopping this medication may cause severe side effects. Alendronic acid, which is a generic drug that is also supplied under the brand name Fosamax Once Weekly (Organon Pharma), is licensed for the treatment of postmenopausal osteoporosis, according to the supply notification. The effects of alendronic acid may occur after 1 month of taking it. This was after I had in some detail again described to him how prior to a jerking episode, my muscles pulled tighter and tighter before a violent release .. he metaphorically patted me on the head and told me to go and have a massage. Thank you. Both. I am worried about it as it seems to be getting worse. Federal drug regulators and researchers say that Fosamax, a drug thats supposed to help with bone growth, is linked to this rare dental disease thats also called Dead Jaw Syndrome. In fact we were three quarters of the way through our time together before I happened to mention I took alendronic acid. Participants will receive one dose of active zoledronic acid during the first month after heart or liver transplantation and weekly placebo alendronate pills or one dose of placebo zoledronic acid and weekly active alendronate pills for the first year after transplant. What an awful time you are having my sympathy goes out to you. I am also diabetic 2 (no drugs diet only) coeliac (wheat and gluten free. The method comprises the steps of reacting a compound of formula I with H 3 PO 3 wherein R is an imido group and R 1 is selected from the group consisting of chloro, bromo, iodo, fluoro, hydroxy, amino, OR 2 or OC(O)R 2 , wherein R 2 is C 1 -C 12 alkyl, C 1 -C 12 cycloalkyl or C 1 -C 12 aryl; and then reacting the . If I took slow shallow breaths the pain was bearable. What an awful position to be in! 74, fractured hip. Common Fosamax Side Effects I dont think there is enough information from doctors/nurses to explain about Osteoporosis to patients. It is strongly linked to a condition called bisphosphonate related osteo necrosis of the jaw if you require any dental treatment while you take it. Armed with more natural solutions which I have been taking anyway but paying more attention now. This was long ago and it was a new drug but the GMC told my GP that yes there was a slight risk of an allergic reaction to it. So I left the surgery with a prescription for alendronic acid and a promise I would have a scan after two years, not the usual three. Below are essential things that you should know before taking alendronic acid: Tell your doctor if you have any dental implants or any tooth issues before taking alendronic acid. I am at the moment still recovering from my fracture as it only been 3wks so if anyone reading this have a build up of pressure on your leg whilst taking these awful tablets seek help before the leg breaks as it will the femur is so so painful take care everyone. I also had pain/soreness behind the eyes and a niggling headache for 48 hours. She had dizzy spells, blackouts, feeling sick etc and doctors said she had Temperol Arteritis. Both risedronic acid and oral alendronic acid have been shown to prevent bone loss when taken daily. So I duly took the AA70, now on third month. reading all of your comments I will not be taking another one of theses tablets . There is a phrase called the patient financial profile which is the profit made from an illness or disease or condition without the patient either getting cured or dying. After reading about it I returned the box of tabs unused. I have v v mild connective tissue disorder (not rare) also. Please talk to your doctor about this. Exercise and healthy food and some good supplements. Im 61 and after a long history of fractures (mostly sports related) and a recent wrist fracture from a fall, I had a DXA scan and have Oseopenia. Even before Fosamax was introduced in 1995 as a superior osteoporosis treatment, jaw osteonecrosis has been linked to the bisphosphonate drug family. I am 70 and keep fit by walking everywhere. Newsletter archive, Data Based Medicine Global Ltd. She told me that all of these drugs, which is just a few, would cause me to have the same side effects. But, theres not enough evidence on this claim. Delighted to report Tum is behaving much better since giving up just hoping the other side effects ( Jaw and Teeth) dont show up unexpected! the pain in my muscles and bones is unbearable, chills, last I had night sweat, my stomach was bloated, acid reflex and the headache along with my jaw ache wont go away. Then in early November I started to feel strange again. . Ive been prescribed Adcal-D3 tablets (2x twice daily) and Alendronic Acid 1x weekly, even though a blood test showed that my calcium and vitamin D levels were within the normal range. Took dose 7, and on and off right hip aches, but now radiating to thigh. Alendronate (alendronic acid) Alendronate is an osteoporosis medication. After reading the comments I will not be taking it again. My memory was a little fuzzy. I hope you are ok. Singing, to my deep distress, is now out of the question, along with all the other active things I loved to do. Now its probable to be loosing my teeth and I live on social security and am very afraid that my dental health has been irrevocably damaged by this drug. Having read all the above I am going to see my doctor again about this drug. In April 2010 I went back to my gym routine, and within a few weeks the second jerking episode occurred. Burning chest pain, sore throat and pains all over. Take the medicine on an empty stomach. Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. Now have constant If you suddenly stop taking the drug, you might experience severe side effects, putting you at high risk of more bone fractures. Whenever Ive mentioned it to my GP, its sort of brushed away. Clinical trial results suggest an increased risk of atrial fibrillation for zoledronic acid (Aclasta ), pamidronic acid, and possibly for alendronic acid, although the balance-risk remains. From day one my tummy was not happy & after 8 weeks I suddenly became severely constipated (Literally overnight !!!) Brand Names Adrovance, Binosto, Fosamax, Fosamax Plus D, Fosavance Generic Name Alendronic acid DrugBank Accession Number DB00630 Background There is a fine balance struck in order to treat symptoms without curing, so your symptoms are only abated when you take drugs, but if you die, then obviously they make no more money. I dont know if these problems have been caused by the AA, but Im now thinking that I should stop taking it and see if my symptoms resolve. I have also been taking Adcal tablets for years. Fast forward to 2008. Two or three times a week. For alendronic acid Common or very common Gastrointestinal disorders; joint swelling; vertigo Uncommon Haemorrhage Rare or very rare Femoral stress fracture; oropharyngeal ulceration; photosensitivity reaction; severe cutaneous adverse reactions (SCARs) Side-effects, further information It got better in the day, but flared up at night for a few nights, then resolved. Stopped alendronic acid for two years during which time I broke my femur in 2014 Hospital June 2014 Spine-2.5 Hip -0.9 Started alendronic acid Jul 2014 for three years Hospital Aug 2017 Spine -2.7 Hip -1.1 Although the scores looked very slightly better at the start they more or less stayed the same for years. For all patients: Dental practitioners should ask about current or past use of Theres little research if alendronic acid is safe for breastfeeding moms. I will not be taking another one! Carole, you say you were meant to have another scan in 3 years, that is disgraceful that you have not had this. I too am very healthy woman 67, play golf dance swim walk, so I was upset to be told I had osteoporosis. Im also having episodes of increased heart rate on a regular basis just from walking a short distance. The GP has been renewing this prescription although I now read a patient only needs to take for 2 yrs max! I dont know if this is due to alendronic acid or the letrozole I am taking for breast cancer. I called my doctor and will go in tomorrow morning, even though pain resolved. Your doctor might recommend you take other drugs 30 minutes after taking alendronic acid. It has given me bad acid reflux. I chose the infusions and, after two infusions, the Pagets was seen to be in remission. Fosamax (alendronic acid) is used to treat osteoporosis. In 2002 I discovered via the internet that I wasnt desperately ill with an anxiety disorder that only Seroxat could fix. Alendronate may also be used for purposes not listed in this medication guide. You can, however, lie down after youve eaten your first meal of the day. As far as the AA, its track record shows there have been dental issues in some people. HI all I fractured my wrist in October had a dxa scan and was told I had osteoporosis. I also ate one energice bar. I was told that it was very uncommon what happened to me, and it was my choice to take it again next week or not. I have gone downhill and increased weight. Whoa, I said, I want to do this with diet and exercise. I asked her how long wil it take for the fosamax to leave my body, and when will this pain stop. Sight has deteriorated (but attend Moorfields for regular check ups. So, what happens now, does my Osteoporosis get progressively worse over time? My legs and bottoms of feet, are so painful. She had to wait months and eventually had the hip replacement. Im going to stop taking Alendronic acid. ). My face had also experienced this and I have had swollen lips. I was determined that my own actions would build my bones so I only had to take the drug for a short time. 20 mile house bernadette 0533 929 10 81; best time to visit kodiak island info@reklamcnr.com; grateful dead from the vault box set caner@reklamcnr.com; athens high school basketball roster reklamcnr20@gmail.com http://www.drugwatch.com/fosamax/osteonecrosis/, Fosamax is linked to osteonecrosis, or bone death, of the jaw. The current protocol for this drug is for 3-5 years maximum. I also found a naturally sourced alternative to the calcium, which is much easier to digest, but its not as strong. Hi Everyone I took the tab yesterday &.the strange & heavy uneven rhythm actually woke me up last night. A blood test followed and the inflammation was evident in the test, but I did not test positive for RA which I was worried about. The last two weeks I have felt terribly sick, not eaten much had terrible bloated stomach, one Sunday I felt so ill I had to do a 111 saw a medical person and was given a thorough test being told everthing was ok, I had put it all down to my gallbladder which it wasnt. Already taking Adcal D3 and steroids. I was such an idiot for believing in this drug! Learn more. judy. Then seen a doctor over the pains in my head he asked how long Id been taking alendronic when I told him how long Id on them, he was horrified and reported straight away.They discovered I had broken Vertebrae leaning on my spinal cord.Alendronic should be band. I tried the Alendronic acid one a week tablet last night and was so unwell that I nearly called an ambulance, my symptoms were very cold ie chattering teeth, pains all over body, sore head,jerking arms and very unsteady on feet, and nausea. I also have arthritis in my thumbs. Anyway, I started to take them three weeks ago and I seem to have been fortunate in that I have had very few side effects but, after reading all these reviews, Im not sure I will carry on as Im fit and healthy with no pain. I have just taken my first one and reading this forum is really interesting. I started reading this because after being diagnosed with breast cancer part of my ongoing treatment is Letrozole plus Alendronic Acid. Are we not sentient beingsthey are not the be all and end all. I had a fall/fracture side of leg then DEXA scab and told I had osteoporosis, my reading was -2.6 which I believe is just over normal readings. Other symptoms include numbness of the lips which are also dry and sometimes numbness in the chin. My mom who is 76 has taken 7 tablets, she stopped due to pain in her hips legs and groin. Shingles 6 months ago and Dr. says this is result of shingles. Im very concerned, like you & so many others, about the side effects of AA which I have just started today! Since taking alendronic, I have had difficulty in running and doing all the workout I was doing. My GP told me to take alendronic acid with the calcium and vit D tabs 5 or so years ago (in my mid 40s), after a DEXA scan showed I had mild osteoporosis already. Energice is a vitamin infused Premium Isotonic ice bar scientifically formulated with Electrolytes, B Vitamins (B3, B5, B6, B12) and Potassium. Ive only just started on the AA but since my run in with Metoclopramide Im scared to take any drugs now. Results are insufficient to support the use of alendronic acid in paediatric patients with osteogenesis imperfect. Its essential to take calcium supplements and vitamin D3 at least 2-4 hours before your first dose of alendronic acid. This is a condition that causes your bones to get weaker and be more likely to break. I decided to stop. The dentist recommend my mom to have all teeth in the lower jaw removed (some are already loose) and get denture. Thank all of you for your posts. Everything was find. This vitamin helps your bones absorb more calcium. I called my doctor and spoke with the nurse. September 2020 Diagnosed with PMR & prescribed Prednisolone + ADCAL3D +Alendronic Acid. In addition, you should cut down on your alcohol intake, stop smoking, do strength training and supplement your body with calcium and vitamin D3, K2, and magnesium regularly. Am I the only one the suffer from these bad side effects after taking it for the first time. It starts after some seemingly minor jaw trauma, but jaw osteonecrosis can quickly decimate a jawbone. Ive been taking Alendronic Acid and Adcal for just over four years and a couple of times felt that my lower face looked slightly strange, nobody else could really tell and it didnt happen that often.
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alendronic acid has destroyed my life